References of interest

From Nature Medicine 5th August 2015

• Germs and joints: the contribution of the human microbiome to rheumatoid arthritis pp839 – 841
  Geraint B Rogers
  doi:10.1038/nm.3916

  Rheumatoid arthritis (RA) is a debilitating autoimmune disorder, the etiology of which is poorly understood. A new study reveals dysbiosis in gut and oral microbiomes of affected individuals, potentially providing a basis for patient stratification and clues to pathophysiological mechanisms of RA onset and progression.

• The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment pp895 – 905
  Xuan Zhang, Dongya Zhang, Huijue Jia, Qiang Feng, Donghui Wang et al.
  doi:10.1038/nm.3914

  The gut and oral microbiomes are altered in individuals with rheumatoid arthritis, and these changes can be used to stratify individuals for diagnostic and prognostic purposes.